Extended Data Fig. 5: CaMs potently desensitize the Glu-induced activity of GLR3.3 channel.

a Representative time-lapse images of Glu-activated [Ca2+]cyt increases in COS-7 cells expressing GLR3.3, CaM2, CaM7, or their combinations. b Representative time-lapse images of Glu-activated [Ca2+]cyt increases in COS-7 cells expressing CaM7, GLR3.3, GLR3.3-CD2 (harboring CBD-deleted CTD), or their combinations. Scale bar = 50 μm. Representative images are shown from more than eight biological replicates. Related to Fig. 3.