Extended Data Fig. 2: Structural comparison of sNSV L Endonucleases. | Nature Plants

Extended Data Fig. 2: Structural comparison of sNSV L Endonucleases.

From: Structural basis for the activation of plant bunyavirus replication machinery and its dual-targeted inhibition by ribavirin

Extended Data Fig. 2: Structural comparison of sNSV L Endonucleases.

Endonuclease region of TSWV L (a), LACV L (b), SFTSV L (c), LASV L (d) and FluA polymerase (e): schematic representation (top) and structure (bottom). Corresponding structural elements are presented in the same color. The side chains of the key motif that constitute the active site are displayed as orange sticks. f, N-lobe of TSWV endo and an iron binding protein (PDB ID: 6N63) exhibit a remarkably high degree of structural similarity.

Back to article page