Extended Data Fig. 3: Large inversions among the six ‘Tanzania’ haplotypes supported by Hi-C contact signals and HiFi read alignments.

The example shown here is the 5.68-Mb inversion on ‘Tanzania’ chromosome 12 F. a, Heatmap of the Hi-C contact signals among the six haplotypes of ‘Tanzania’, supporting the inversion on chromosome 12 F. b, HiFi read alignments using TznChr12F as the reference. Reads spanning the inversion breakpoints at TznChr12F 11.8 Mb and 17.5 Mb, which originated from haplotype TznChr12F, are highlighted by the green boxes. Reads that are split-aligned, which originated from the other five haplotypes, are highlighted by orange boxes.