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Spatial transcriptomics decodes the cellular landscape of plant–pathogen interaction

This study uses single-cell spatial transcriptomics to explore the early interactions between potato leaf cells and the pathogen Phytophthora infestans, revealing cellular heterogeneity in gene expression at the infection site and providing a valuable resource for future enhancement of potato disease resistance.

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Fig. 1: Functional specialization of PTCs and SPCs in the host–microorganism microenvironment.

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This is a summary of: Li, Y. et al. Host microenvironment in potato–Phytophthora infestans interaction revealed by single-cell spatiotemporal transcriptome. Nat. Plants https://doi.org/10.1038/s41477-025-02181-9 (2026).

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Spatial transcriptomics decodes the cellular landscape of plant–pathogen interaction. Nat. Plants 12, 10–11 (2026). https://doi.org/10.1038/s41477-025-02204-5

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