Fig. 2 | npj Aging and Mechanisms of Disease

Fig. 2

From: Functionally and morphologically damaged mitochondria observed in auditory cells under senescence-inducing stress

Fig. 2

Change in mitochondrial morphology in H2O2-exposed cells. Short exposure to H2O2 induces fine structural changes of mitochondria in HEI-OC1 cells. Cells were dyed with TMRE MMP fluorescence. a Control cells captured with confocal microscopy. The form of the mitochondria is string shaped (Scale bar, 10 μm). b H2O2-exposed cells. The shape of the mitochondria is segmented in small balloon shape (Scale bar, 10 μm). c Control cells captured with N-SIM (Scale bar, 5 μm, Small box, 2 times magnified image). d Cells exposed to H2O2 and captured with N-SIM. The thickness of the mitochondria is larger than the control cells (Scale bar, 5 μm, Small box, 2 times magnified image)

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