Fig. 7
From: Conserved and species-specific molecular denominators in mammalian skeletal muscle aging
Increased oxidative stress and inflammation are observed with age among species. a Oxidative stress markers (4-HNE and protein carbonylation) in skeletal muscle of mice (M), rhesus monkeys (Rh), and humans (H). b Inflammatory mRNA markers (TNF-α, IL-1β, IL-6, and IL-10) analyzed by quantitative RT-PCR in skeletal muscle of mice (M), rhesus monkeys (Rh), and humans (H). Relative expression values were normalized to young within each species. c Immunoblot of pNF-κB and NF-κB in skeletal muscle of young (Y), middle-aged (M), and old (O) mice, rhesus monkeys and humans. d Immunoblot of COX2 in human skeletal muscle of young (Y), middle-aged (M), and old (O) individuals. *p < 0.05 vs. young. Values are expressed as mean ± SEM. *p < 0.05 vs. young
