Table 2 Baseline characteristics of the unpaired cross-sectional study

No-statin-No-PCSK9 group

Statin group

PCSK9 group

P-value

(n = 41)

(n = 60)

(n = 19)

Mean age (year)

64.6 ± 10.7

65.7 ± 5.0

64.1 ± 7.9

0.7738

Male sex (%)

51

65

32

0.0310

BMI (kg/m²)

24.0 ± 4.3

24.8 ± 3.6

24.2 ± 2.7

0.6065

Rate of hypertension treatment (%)

27

30

26

0.9298

Smoking (%)

7

3

0

0.0456

Past history of coronary heart disease (%)

13

39

56

0.0010

Family history of coronary heart disease (%)

20

37

47

0.0572

Systolic bood pressure (mmHg)

135 (91–170)

134 (90–168)

141 (94–164)

0.9201

Diastolic bood pressure (mmHg)

84 (60–100)

83 (59–99)

86 (58–98)

0.9104

Plasma glucose (mg/dL)

124.3 ± 41.0

127.8 ± 41.7

121.0 ± 28.6

0.8200

Hemoglobin A1c (%)

6.14 ± 0.94

6.28 ± 0.81

6.09 ± 0.80

0.7218

Total cholesterol (mg/dL)

201.2 ± 57.5

178.4 ± 46.5

176.7 ± 46.4

0.1829

Triglyceride (mg/dL)

163.8 ± 99.5

192.7 ± 237.4

188.1 ± 96.0

0.7974

High density lipoprotein-cholesterol (mg/dL)

54.7 ± 13.3

54.7 ± 12.4

58.7 ± 12.8

0.5125

Low density lipoprotein-cholesterol (mg/dL)

114.8 ± 53.7

91.4 ± 37.9

79.2 ± 41.6

0.0213

Lp(a) (mg/dL)

7.8 ± 9.7

22.4 ± 22.6

26.0 ± 33.1

0.4678