Table 1 Compartments created in the CellDesigner platform in line with the structure and function of the outer retina.
Outer retina anatomical compartments | Substructures within anatomical compartments | Further subclassification of anatomical structures and organelles | Organelles and deposits in anatomical substructures |
|---|---|---|---|
Choroid | Choriocapillaris | Lumen | Macrophage |
Choriocapillaris | Endothelium | Mitochondria | |
Bruch’s membrane | Outer collagen free zone | ||
Outer collagenous layer | |||
Elastin layer | |||
Inner collagenous layer | |||
Inner collagen free zone | Hard drusen | ||
Soft drusen/basal linear deposit | |||
RPE | RPE basement membrane | Basal laminar deposit | |
Exosome | |||
RPE | Nucleus | ||
Endoplasmic reticulum | |||
Golgi | |||
Mitochondria | |||
Endocytic vesicle | |||
Transcytotic vesicle | |||
Transport vesicle | |||
Early endosome | |||
Recycling endosome | |||
Late endosome | |||
Lysosome | |||
Phagosome | |||
Phagolysosome | |||
Autophagosome | |||
Melanosome | |||
Secretory vesicle | |||
Interphotoreceptor Matrix | Reticular subretinal drusenoid deposit | ||
Macrophage | |||
Photoreceptor | Rod outer segment | Disks | |
Shed rod outer segment | Disks | ||
Cilium | |||
Rod inner segment | Endocytic vesicle | ||
Mitochondria | |||
Endoplasmic reticulum | |||
Nucleus |
