Fig. 2: Morphometric and stereological assessment of mitochondria in white muscle fibers of adult and old mice.

Mitochondrial size and circularity of mitochondria (upper panels) from adult and old sedentary mice or mice subjected to a 4-week daily exercise regimen, HIIT or MICT. Fractional area (FA) of mitochondria and numerical density profiles are depicted in the lower panels. n = 4–5 animals per condition. Data are represented as box and whisker plots, depicting minimum, lower quartile (Q1), median (Q2), upper quartile (Q3), and maximum values. Significance between groups was determined using Two-way ANOVA with Sidak’s post-hoc tests. *p ≤ 0.05; **p ≤ 0.01.