Fig. 2: Receiver operating characteristic curves for distinguishing Aβ+ individuals from Aβ− individuals using plasma sclerostin in combination with the base model (BM) and/or AD-related biomarkers. | npj Aging

Fig. 2: Receiver operating characteristic curves for distinguishing Aβ+ individuals from Aβ− individuals using plasma sclerostin in combination with the base model (BM) and/or AD-related biomarkers.

From: Elevated plasma sclerostin is associated with high brain amyloid-β load in cognitively normal older adults

Fig. 2: Receiver operating characteristic curves for distinguishing Aβ+ individuals from Aβ− individuals using plasma sclerostin in combination with the base model (BM) and/or AD-related biomarkers.

A base model (BM) including age, sex and APOE ε4 carriage status was included in the analysis. Receiver operating characteristic (ROC) curves are presented with the BM (a–e) or without (f–i). a (BM vs BM + SOST), b (BM + p-tau181 vs BM + p-tau181 + SOST), c (BM + p-tau231 vs BM + p-tau231 + SOST), d (BM + GFAP vs BM + GFAP + SOST), e (BM + Aβ1-42/Aβ1-40 vs BM + Aβ1-42/Aβ1-40 + SOST), f (p-tau181 vs p-tau181 + SOST), g (p-tau231 vs p-tau231 + SOST), h (GFAP vs GFAP + SOST) and i (Aβ1-42/Aβ1-40 vs Aβ1-42/Aβ1-40 + SOST).

Back to article page