Fig. 2: Effect of FOXO3 Genotype on Mean Telomerase Activity for Young and Old Participants.
From: Novel protective effect of the FOXO3 longevity genotype on mechanisms of cellular aging in Okinawans
Telomerase activity was measured in PBMC samples using the TRAP assay. Mean telomerase activity for carriers and non-carriers of the longevity-associated FOXO3 G-allele was compared for young (a; age 19–54 years) and old (b; age ≥55 years) participants. Significantly higher levels of telomerase activity were observed in G-allele carriers for old participants (TT = 94, G-allele carriers = 88; P = 0.015) relative to young (TT = 87, G-allele carriers = 59; P = 0.56). (Student’s t-test). Error bars represent standard deviation. Three replicates were performed per sample.
