Fig. 2: SenMayo-hi cells detected in the retinal microglia (Mic). | npj Aging

Fig. 2: SenMayo-hi cells detected in the retinal microglia (Mic).

From: SenMayo transcriptomic senescence panel highlights glial cells in the ageing mouse and human retina

Fig. 2: SenMayo-hi cells detected in the retinal microglia (Mic).The alternative text for this image may have been generated using AI.

a UMAP plot of SenMayo-hi cells in the Mic subcluster. b Top 30 enriched biological processes (BP) in SenMayo-hi Mic, with senescence and immune response-related processes highlighted in blue (FDR < 0.01). See the Supplementary Table 4a for a full list. c Top 20 genes upregulated in the SenMayo-hi Mic (vs SenMayo-low Mic). d Top 30 enriched pathways in SenMayo-hi Mic with senescence-related pathways highlighted in blue (FDR < 0.01). See the Supplementary Table 4b for a full list. e Violin plots depicting increased expression of genes related to AP1 pathway, IL4/13 and IL10signalling in SenMayo-hi Mic.

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