Fig. 6: GDF and TNF signaling are reduced in exercise mice.

a The information flows between the two groups. Left displays the relative proportion changes between the two groups, Right shows the absolute changes in the signaling pathway. b The incoming signaling pattern between the control and exercise group. c Expression of receptor of GDF signaling. P value was calculated using t-test and based on the comparison between the two groups across the entire intestinal crypt. d Levels of cell-cell communication for TNF signaling.