Table 1 Significant changes in protein and RNA transcripts detected in RM33 and the parental strain biofilms

From: Reprioritization of biofilm metabolism is associated with nutrient adaptation and long-term survival of Haemophilus influenzae

NTHI gene #/Name

Function

Protein (fold change)

p value

RNASeq - mean FC

p value

NTHI1768

TrpE

Anthranilate synthase component I

9.1

0.0000003

1.8

1.2E−06

NTHI1763

TrpC

Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase

6.9

0.00012

1.5

1.3E−06

NTHI1702

TrpB

Tryptophan synthase subunit beta

6.9

0.00004

0.4

7.8E−03

NTHI1810

MalQ

Alpha-glucanotransferase

5.3

0.00001

0.3

7.5E−02

NTHI1701

TrpA

Tryptophan synthase subunit alpha

4.8

0.0002

0.1

1.3E−01

NTHI1920

Mao2

Malic enzyme

4.3

0.000003

0.2

8.1E–03

NTHI0202

HemR

Hemin receptor

4.3

0.0004

NS

NS

NTHI0623

AphA

Acid phosphatase/phosphotransferase

4.0

0.000003

NS

NS

NTHI0632

RbsB

D-ribose transporter subunit RbsB

3.8

0.000002

1.6

2.9E−04

NTHI0232

 

Sialic acid transporter, TRAP-type C4-dicarboxylate transport system, periplasmic component

3.6

0.00003

0.0

9.4E−01

NTHI1707

 

ABC transporter periplasmic protein

3.5

0.00001

NS

NS

NTHI0398

SdaC

Serine transporter

3.1

0.00002

1.8

9.3E−03

NTHI1964

SucA

Oxoglutarate dehydrogenase E1

3.0

0.00001

1.8

2.7E−04

NTHI0397

SdaA

l-serine dehydratase

3.0

0.000005

2.1

2.9E−04

NTHI1809

GlgB

Glycogen branching enzyme

3.0

0.00005

2.0

4.2E−03

NTHI0235

 

Acetylneuraminic acid mutarotase

2.8

0.00003

2.0

7.7E−05

NTHI1764

TrpD

Anthranilate phosphoribosyltransferase

2.8

0.0001

0.3

1.8E−09

NTHI1295

 

Carbon starvation protein, membrane protein

2.7

0.0001

1.9

2.7E−04

NTHI1806

GlgA

Glycogen synthase

2.5

0.0002

2.0

2.1E−04

NTHI0647

 

Hypothetical protein

2.4

0.00005

NS

NS

NTHI0660

 

Aspartate ammonia-lyase

2.3

0.00004

0.0

1.8E−01

NTHI1808

GlgX

Glycogen operon protein

2.2

0.00004

2.1

3.7E−04

NTHI1816

Cdd

Cytidine deaminase

2.2

0.0004

0.0

5.2E−01

NTHI1903

 

Folylpolyglutamate synthase

2.1

0.0006

NS

NS

NTHI0610

AtpG

ATP synthase F0F1 subunit gamma

2.1

0.0002

NS

NS

NTHI0973

PckA

Phosphoenolpyruvate carboxykinase

2.0

0.0002

0.1

2.7E−01

NTHI0088

NrdD

Anaerobic ribonucleoside triphosphate reductase

2.0

0.0002

NS

NS

NTHI1028

ClpB

ClpB chaperone

−2.1

0.00003

NS

NS

NTHI0306

AroB

3-dehydroquinate synthase

−3.4

0.00006

NS

NS

Back to article page