Fig. 3: Relative fitness (Fitness index) of the evolved CIP-resistant isolates compared to the ancestor colonies.

a An Inverse correlation (R2 = 0.53) between the lag time and the planktonic fitness index (FI) was observed. b CIP-resistant colonies had a significant (p = 0.0005) better biofilm FI in CIP-exposed biofilms compared to unexposed. Wilcoxon matched-pairs signed ranks was used as statistical test.