Table 1 The types of mutations (number and % of total number of mutations) in CIP and CTRL-resistant colonies in WT PAO1 and ΔkatA biofilm and planktonic (PL) P. aeruginosa.
Transitions | Transversions | Insertions/deletions | Inversions/duplications | Total number of mutations | dN/dS | |
|---|---|---|---|---|---|---|
CIP-resistant colonies | ||||||
PAO1_biofilm | 6 (24%) | 3 (12%) | 13 (52%) | 3 (12%) | 25 | 2.7 |
PAO1_PL | 5 (18%) | 6 (21%) | 13 (46%) | 4 (14%) | 28 | 1.6 |
ΔkatA_biofilm | 157 (78%) | 3 (1.5%) | 43 (21%) | 3 (1%) | 206 | 1.5 |
ΔkatA_PL | 1 (8%) | 3 (25%) | 8 (89%) | 0 | 12 | 0.9 |
CTRL-resistant colonies | ||||||
PAO1_biofilm | 1 (8%) | 5 (42%) | 6 (50%) | 0 | 12 | 2 |
PAO1_PL | 3 (18%) | 0 | 7 (41%) | 7 (41%) | 17 | 1 |
ΔkatA_biofilm | 1 (6%) | 1 (6%) | 14 (82%) | 1 (6%) | 17 | 0.1 |
ΔkatA_PL | 3 (38%) | 0 | 5 (63%) | 0 | 8 | 0.4 |
