Fig. 1: Global transcriptional response of C. glabrata biofilm cells to fluconazole treatment when grown in the presence of glucose (RPMI + fluconazole versus RPMI) or in the presence of both glucose and acetate (RPMI + acetate + fluconazole versus RPMI + acetate).

a Heatmap of all genes differentially expressed (p < 0.05) in the presence versus the absence of fluconazole in both growth conditions. b Venn diagrams of downregulated (decrease of twofold or lower) and upregulated (greater than twofold) genes in C. glabrata biofilm cells due to fluconazole treatment in both growth conditions.