Fig. 3: Post-bronchodilator FVC response and 6-min walk distance correlate with variation in lung bacterial composition along principal component 1, which explained 23.5% of the total variation in lung bacterial community structure among ever-smokers. | npj Biofilms and Microbiomes

Fig. 3: Post-bronchodilator FVC response and 6-min walk distance correlate with variation in lung bacterial composition along principal component 1, which explained 23.5% of the total variation in lung bacterial community structure among ever-smokers.

From: Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort

Fig. 3

Each dot represents an individual BAL sample and is colored according to its PC score. OTUs contributing significantly (q-value < 0.10) to PC1 are shown in the accompanying table, ranked by Pearson’s correlation coefficient. The relative abundances of Prevotella, Pseudomonas, and Streptococcus are primary drivers of PC1 variation. a Post-bronchodilator FVC response measured by change in percent and volume in mL. b Six-minute walk distance (meters).

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