Fig. 8: Application of fecal microbiota transplantation (FMT) for the therapeutic modulation of diseased microbiota. | npj Biofilms and Microbiomes

Fig. 8: Application of fecal microbiota transplantation (FMT) for the therapeutic modulation of diseased microbiota.

From: Daily full spectrum light exposure prevents food allergy-like allergic diarrhea by modulating vitamin D3 and microbiota composition

Fig. 8

a Therapeutic modulation of gut microbiota by FMT in FA mice. After the development of FA and following antibiotic-induced dysbiosis, FMT with control donor feces (control-FMT) was administered to FA mice (n = 10). FA mice without FMT (n = 5) were set as a comparison. Allergic diarrhea was assessed visually by monitoring mice for 30 min after each i.g. exposure. **P < 0.01 vs. FA mice without FMT (Tukey’s multiple comparisons test). b Histological evaluation of the intestines of FA mice with/without control-FMT after the 6th OVA challenge. The pictures at ×100 magnification are representative of ten individuals in each group. H&E hematoxylin and eosin staining. Scale bar: 100 μm. c Reduced expression of total and OVA-specific IgE after the 6th OVA challenge in FA mice with control-FMT (white bar). Black bar: FA mice without FMT. Values are presented as the mean ± SD of ten individuals in each group. *, **, P < 0.05 and 0.01 vs. FA mice before FMT or the indicated pair, respectively (Student’s t test).

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