Fig. 1: Simulation and measurements of intermittent alternating magnetic field (iAMF) heating.
From: Alternating magnetic fields and antibiotics eradicate biofilm on metal in a synergistic fashion
The experimental set-up consisted of a stainless-steel ring with biofilm in media in a 50-mL tube and held in place by a plastic holder (a left image). The tube is placed in a solenoid coil (a right image). b shows a representation of the iAMF dosing scheme. An iAMF treatment was organized as a series of doses separated by hours (Ītdose, panel top). Ndose was the number of doses in the whole treatment. Each dose is composed of multiple short-term exposures of AMF (Nexp). During the iAMF exposure, the AMF was on for several seconds of (texp), and the rings were heated to the targeted temperature (Tmax). The exposures were delivered at intervals (Ītexp) to allow the temperature to return to baseline (b middle image). Temperature vs. time for the ring upon AMF exposure to a Tmax of 50, 65, and 80āĀ°C is shown c. Simulated AMF heating of a metal ring for different exposure times depicts spatial temperature variation on the surface, and minimal heating of surrounding media. The mean and standard deviation of the temperature are shown.
