Fig. 4: Diversity of microbial genes associated with associated with EC numbers.
From: Periodontitis associates with species-specific gene expression of the oral microbiota
a α-diversity of gene families found in metagenomes (DNA) and metatranscriptomes (RNA) in plaque, tongue biofilm, and saliva expressed as number of observed gene families (i.e., richness). Boxplots display first quartile, median, and third quartile and whiskers represent 1.5 times the interquartile range from the first and third quartiles. b β-diversity of gene expression visualized as measured by log RNA/DNA ratio quantified using weighted Jaccard distance and visualized on PCoA. Sample denotation: red: periodontitis, blue: oral health, circle: plaque, triangle: tongue biofilm, square: saliva. Significant differences were assessed using Kruskal–Wallis and PERMANOVAS tests for α and β-diversity, respectively. Significant FDR-adjusted p values were indicated as follows: *0.05 > p > 0.01 **0.01 > p > 0.001 ***p < 0.001.
