Table 2 AMP therapeutic indexes (TI): corresponding to the fold difference between IC50, with standard deviation (+/−).

From: Microbiome-derived antimicrobial peptides offer therapeutic solutions for the treatment of Pseudomonas aeruginosa infections

 

IC50 on BEAS (µg/ml)

IC50 on IMR90 (µg/ml)

MIC against PA01 (µg/ml)

MIC against LES431 (µg/ml)

Lower TI

Higher TI

Mean TI

Lynronne 1

138.9 + /− 34.1

94.2 + /− 21.7

32

8

2.9

17.3

10.1

Lynronne 2

1177 + /− 309.2

803.2 + /− 202.8

64

16

12.5

73.5

43.0

P15s

3337 + /− 882.3

948.9 + /− 224.0

64

128

7.4

52.1

29.7

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