Fig. 7: Histological evaluation of organ injuries in E. faecalis-infected mice treated with LL-37 and/or Ply2660. | npj Biofilms and Microbiomes

Fig. 7: Histological evaluation of organ injuries in E. faecalis-infected mice treated with LL-37 and/or Ply2660.

From: Bactericidal synergism between phage endolysin Ply2660 and cathelicidin LL-37 against vancomycin-resistant Enterococcus faecalis biofilms

Fig. 7

a Samples of the lung, liver, and kidney from mice with different treatments were fixed in 4% formalin, and tissue sections were prepared for H&E staining. Scale bars, 50 μm. Pathological scores of the b lung, c liver, and d kidney were evaluated from three random fields by two independent scientists. The data are presented as the means ± SD; error bars represent the standard deviation. Statistical significance was calculated using one-way ANOVA followed by Tukey’s multiple comparison test. *P < 0.05; **P < 0.01; ***P < 0.001; ns, not significant.

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