Fig. 11: Orthogonal projections to latent structures discriminant analysis (OPLS-DA) of cervicovaginal fluid samples of preterm- and term-delivered women between gestational time points (GTPs) 1 and 2. | npj Biofilms and Microbiomes

Fig. 11: Orthogonal projections to latent structures discriminant analysis (OPLS-DA) of cervicovaginal fluid samples of preterm- and term-delivered women between gestational time points (GTPs) 1 and 2.

From: Vaginal host immune-microbiome-metabolite interactions associated with spontaneous preterm birth in a predominantly white cohort

Fig. 11

a Positive ionisation mode that detects peaks corresponding to protonated metabolites. b Negative ionisation mode, which detects peaks corresponding to deprotonated metabolites. A clear separation was observed between GTP 1 and 2 in the term-delivered women (negative ionisation mode). Whereas, a similar but less distinct trend was observed in the preterm-delivered women perhaps due to the relatively smaller number of samples. GTP1 (n = 49) and GTP2 (n = 45).

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