Fig. 5: Orthogonal projections to latent structures discriminant analysis (OPLS-DA) of cervicovaginal fluid samples of preterm- and term-delivered women at gestational time point (GTP) 1 (20–22 weeks, n = 49). | npj Biofilms and Microbiomes

Fig. 5: Orthogonal projections to latent structures discriminant analysis (OPLS-DA) of cervicovaginal fluid samples of preterm- and term-delivered women at gestational time point (GTP) 1 (20–22 weeks, n = 49).

From: Vaginal host immune-microbiome-metabolite interactions associated with spontaneous preterm birth in a predominantly white cohort

Fig. 5

a Positive ionisation mode that detects peaks corresponding to protonated metabolites. b Negative ionisation mode, which detects peaks corresponding to deprotonated metabolites. c Fold change of metabolites that differ between preterm- vs. term-delivered women at GTP1. All the metabolites were upregulated in the women who delivered preterm except isobutrin (Welch’s t-test).

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