Fig. 7: Orthogonal projections to latent structures discriminant analysis (OPLS-DA) of cervicovaginal fluid samples of preterm- and term-delivered women at gestational time point (GTP) 2 (26–28 weeks, n = 45). | npj Biofilms and Microbiomes

Fig. 7: Orthogonal projections to latent structures discriminant analysis (OPLS-DA) of cervicovaginal fluid samples of preterm- and term-delivered women at gestational time point (GTP) 2 (26–28 weeks, n = 45).

From: Vaginal host immune-microbiome-metabolite interactions associated with spontaneous preterm birth in a predominantly white cohort

Fig. 7

a Positive ionisation mode that detects peaks corresponding to protonated metabolites. b Negative ionisation mode, which detects peaks corresponding to deprotonated metabolites. c Fold change of metabolites that differ between preterm- vs. term-delivered women at GTP2. All the metabolites were upregulated in the women who delivered preterm compared to their term-delivered counterparts (Welch’s t-test). d and e Receiver operating characteristic curve analysis of the performance of pantothenate and phytoene for prediction of spontaneous preterm birth at GTP2 (Term = 31, Preterm = 14). AUC area under the ROC curve (95% confidence interval).

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