Table 11 Cervicovaginal metabolite changes from GTP1 to GTP2 in preterm- and term-delivered women by ANOVA

Nonacosane

0.008

C08384

• Component of pheromone

• Chemical communication¹²¹

Adenosine

0.012

C00212

• Energy transfer

• Signal transduction

• Neurotransmitter

• Vasodilator

• Immunotoxin

• Metabotoxin

(HMDB0000050)

Deoxyguanosine

0.012

C00330

• Inherited metabolic disorder (Purine nucleoside phosphorylase (PNP) deficiency)¹²²

Dehydrosafynol

0.014

C08447

Anit-inflammatory¹²³

Cycloartenol

0.029

C01902

• Anti-inflammatory¹²⁴

Lanosterol

0.029

C01724

• Animal and fungal sterol biosynthesis¹²⁵

Phytoene

0.029

C05413

• Anti-oxidant

• Anti-inflammatory^109,110

Phytofluene

0.043

C05414

Isoliquiritigen

0.037

HMDB0037318

• Enhance antitumor activity of cyclophosphamide¹²⁶

Giganin

0.041

C08488

• Cytotoxic

• inhibits mitochondrial electron transport systems¹²⁷

Urate

0.022

C00366

• Anti-oxidant

• Marker of PTB^102,103

Jervine

0.049

C10811

• Anti-inflammatory, anti-tumour, anti-platelet, and anti-adipogenic agent^128,129

Thiamine

0.049

C00378

• Vitamin B1

• Intracellular glucose metabolism

• Antioxidant

• Erythropoietic

• cognition-and mood-modulator

• Antiatherosclerotic

• Putative ergogenic

• Detoxification activities

(HMDB0000235)