Fig. 6: Investigating within-sample induction and contributions of environmental factors.

Comparing all samples’ viromes mapped against prophage contigs assembled in same vs other samples, expressed as sample-wise A mean induction rate (ie per-sample mean of prophages that were significantly induced in same vs other samples), B Median number of reads mapped to contig (per-sample mean of same vs other), and C Median reads per kilobase (RPK); i.e. length-adjusted mapping rate. D Analysis of within-sample vs between-sample induction estimates adjusted for number of reads mapped to contig, showing that especially contigs with high mapping rates exhibit high rates of induction. Rates of all virome-contig matches are summarized within bins of the number of total reads per contig. E Comparison of sample-wise induction rates split in sample-matched and non-matched virome-contig pairs, comparing samples according to key environmental factors. Children with siblings exhibit lower rates of induction compared to those without siblings.