Fig. 1: Study overview.
From: Tanzanian gut microbiota profiles linked to high but rapidly waning yellow fever antibody titers
a Geographic map of study sites in Tanzania (Moshi Urban and Moshi Rural), within the Kilimanjaro region. b Graphical representation of the number of urban and rural living participants included in the study and of those from whom stool samples for microbiota assays were available, stratified by the total number of participants (N) and the number of individuals who received the yellow fever (YF-17D) vaccine (Nvacc). c Study design and number of samples at each time point. Numbers depicted as n (nvacc), i.e. total number of samples (number of samples from vaccinated individuals). The number of samples in which neutralizing antibodies were measured only includes those samples with a matching stool sample. d Graphical summary of study analyses. Questionnaire data from all included individuals (N = 185) were used in multiple correspondence analyses (MCA)/principal component analyses (PCA) to derive lifestyle/food scores. The associations between microbiota profiles and demographics and lifestyle factors (summarized in scores) and vaccine responses were assessed.
