Table 2 MIC values of the active trisindolines against MDR clinical isolates of S. aureus
S. No. | MDR-clinical isolates | MIC of the active Trisindolines, µg/ml | |||||||
|---|---|---|---|---|---|---|---|---|---|
3b | 3c | 3d | 3e | 3g | 3l | 3n | 3o | ||
1 | SA-01 | 4.9 | 2.6 | 2.6 | 6.5 | 2.7 | 44.8 | 2.7 | 11.6 |
2 | SA-02 | 19.9 | 43 | >43 | 51.7 | 44.2 | 44.8 | 44.4 | 23.2 |
3 | SA-03 | 4.9 | 1.3 | 2.6 | 6.5 | 5.2 | 5.6 | 2.7 | 5.8 |
4 | SA-04 | >39.8 | 43 | >43 | >51.7 | >44.2 | >44.8 | >44.4 | >46.4 |
5 | SA-05 | >39.8 | >43 | >43 | >51.7 | >44.2 | >44.8 | >44.4 | >46.4 |
6 | SA-06 | 4.9 | 1.3 | 5.4 | 1.6 | 5.2 | 5.6 | 2.7 | 2.8 |
7 | SA-07 | 4.9 | 0.6 | 0.6 | 3.2 | 0.6 | 5.6 | 0.6 | 5.8 |
8 | SA-08 | >39.8 | >43 | >43 | >51.7 | >44.2 | >44.8 | >44.4 | >46.4 |
9 | SA-09 | >39.8 | 43 | 43 | 25.8 | 44.2 | 44.8 | 44.4 | 23.2 |
10 | SA-10 | >39.8 | >43 | >43 | >51.7 | >44.2 | >44.8 | >44.4 | >46.4 |
11 | SA-11 | 4.9 | 0.6 | 0.6 | 1.6 | 0.6 | 5.6 | 0.6 | 2.8 |
12 | SA-12 | 2.4 | 1.3 | 1.3 | 6.5 | 5.2 | 5.6 | 11.1 | 5.8 |
13 | SA-13 | 39.8 | 21.5 | 21.5 | 51.7 | 44.2 | 44.8 | 44.4 | 46.4 |
14 | SA-14 | 19.9 | 21.5 | 21.5 | 25.8 | 22.1 | 22.4 | 22.2 | 11.6 |
15 | SA-15 | >39.8 | >43 | >43 | >51.7 | >44.2 | >44.8 | >44.4 | >46.4 |
16 | SA-16 | 4.9 | 0.6 | 1.3 | 6.5 | 0.6 | 5.6 | 0.6 | 2.8 |
17 | SA-17 | 4.9 | 0.6 | 5.4 | 3.2 | 0.6 | 2.7 | 0.6 | 5.8 |
18 | SA-18 | 19.9 | 43 | 21.5 | 51.7 | 44.2 | >44.8 | >44.4 | 23.2 |
19 | SA-19 | 19.9 | 21.5 | 43 | 25.8 | 44.2 | 22.4 | 44.4 | 46.4 |
20 | SA-20 | >39.8 | 21.5 | 21.5 | 51.7 | 44.2 | 22.4 | 22.2 | 23.2 |
21 | SA-21 | 39.8 | 21.5 | 43 | 25.8 | 44.2 | 22.4 | 22.2 | 23.2 |