Fig. 1: Candida albicans persists in the microbiome-free environment of the M-SHIME®, under simulated proximal colon physiological conditions.

Concentrations were measured by qPCR (n = 3), and data are represented as mean ± standard deviation. Candida albicans strain SC5314 was inoculated at days 0, 2, and 8, in a sterile bioreactor, as indicated by red asterisks. The limit of quantification ( = LOQ) is indicated with a dotted line.