Table 3 MIC values (μg/mL) for the two new AMPs discovered (Pcin-CATH3 and Pcin-CATH5) from P. cinereus transcriptomic data

From: Novel antimicrobial peptides and peptide-microbiome crosstalk in Appalachian salamander skin

 

E. faecium

S. aureus

K. pneumoniae

A. baumannii

P. aeruginosa

E. cloacae

E. coli

Compound ID

19434

49224

25923

43300

700603

13883

4640

17978

19606

5075

PA01

27853

5519

13047

35549

35218

43888

Pcin-CATH3 (Tr-Pc3)

>128

>128

>128

>128

>128

>128

>128

64

64

16

32

>128

>128

>128

>128

>128

64

Pcin-CATH5 (Tr-Pc5)

64

64

>128

64

>128

>128

>128

8

8

4

16

>128

>128

>128

>128

32

16

LL-37

32

32

>128

>128

32

4

64

4

2

4

4

8

16

64

4

8

8

Levofloxacin

4

2

0.25

0.25

0.5

0.25

32

0.25

0.25

4

8

0.5

32

0.25

0.25

0.25

0.25

  1. LL-37 and Levofloxacin were used as positive controls. Strain IDs for the ESKAPEE panel are indicated below each bacterial species.