Fig. 2: 2bRAD-M revealed highly accurate microbiota composition in HoC mock samples.
From: High-resolution microbiome analysis of host-rich samples using 2bRAD-M without host depletion
In both (a) and (b), the left panel shows the taxonomic profiling results of MSA 1002 mixed with 90% human DNA, while the right panel shows results from MSA 1002 mixed with 99% human DNA. In the stacked bar plots, the colored bars indicate bacteria taxa present in the ground truth, while the white bars indicate false positives identified in the profiling results of a given method. AUPR measures the accuracy of microbial identification, and L2 similarity measures the similarity between the ground truth and predicted taxonomic profiles. a Genus-level profiling results of the three sequencing methods (16S, 2bRAD-M, WMS) on the same DNA mock community (MSA 1002). b Species-level profiling results of the three metagenomics methods.
