Fig. 3: Synthesis of ceramides by intestinal bacteria of Marmota himalayana during hibernation. | npj Biofilms and Microbiomes

Fig. 3: Synthesis of ceramides by intestinal bacteria of Marmota himalayana during hibernation.

From: Intestinal bacteria trigger a hibernation-like state in homotherms via the gut-brain axis

Fig. 3

Fatty acid biosynthesis (A), serine metabolism (B), and sphingolipid metabolism (C) in intestinal bacteria of active (green, n = 3) and hibernating marmots (pink, n = 3). All bar graphs depict means ± standard errors of the mean. Two-tailed unpaired t-tests (A–C) were used to detect statistical significance. *p < 0.05, **p < 0.01, ***p < 0.001. fabH 3-oxoacyl-[ACP] synthase III, fabZ 3-hydroxyacyl-[ACP] dehydratase, fabK Enoyl-[ACP] reductase II, ACSL Long-chain acyl-CoA synthetase, serB phosphoserine phosphatase, GBA Glucosylceramidase, lacZ beta-galactosidase.

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