Fig. 6: Responses of colonic barrier function, oxidative stress, and SCFAs to dietary copper supplementation. | npj Biofilms and Microbiomes

Fig. 6: Responses of colonic barrier function, oxidative stress, and SCFAs to dietary copper supplementation.

From: Dietary copper-driven colonic dysbiosis mediates oxidative stress and butyrate deficiency to facilitate the spread of resistome in pigs

Fig. 6: Responses of colonic barrier function, oxidative stress, and SCFAs to dietary copper supplementation.The alternative text for this image may have been generated using AI.

A H&E-stained colonic sections of three groups. B Histopathological scores of colons. n = 6 piglets/group. C Copper contents within colonic digesta. D Western blot of MUC2, ZO-1, and E-cadherin in the colon. E Fold change of the Fluorescence intensity relating to ROS levels (E) and MDA Production (F) within colon and serum. G Butyrate concentration in colonic digesta. CON, control group; CS, copper sulfate group; CP, copper-peptide group. Values are shown as means and error bars represent SEM. Statistical significance was determined using One-way ANOVA with Tukey’s test.

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