Table 2 Performance of the 95-gene residual risk signature and multiparametric tests in the validation cohort

From: Molecular stratification of early breast cancer identifies drug targets to drive stratified medicine

 

HR

HR.95L

HR.95U

P

N

AUC

95-Gene Signature

5.045

3.528

7.215

7.51 × 10−19

1924

0.76

MammaPrint-like

3.631

2.765

4.767

1.66 × 10−20

1973

0.72

Prosigna-like

3.49

2.592

4.699

1.75 × 10−16

1971

0.70

IHC4-RNA

3.475

2.346

5.148

5.11 × 10−10

1973

0.72

Genomic Grade Index-like

3.118

2.341

4.153

7.51 × 10−15

1973

0.67

OncotypeDX-like

2.969

2.232

3.948

7.37 × 10−14

1973

0.71

IHC4-Protein

2.398

1.851

3.108

3.72 × 10−11

1855

0.68