Table 1 Baseline characteristics of ViDA participants who consented to abdominal adipose biopsy (AB) and/or random fine needle periareolar aspiration (RPFNA)
All ViDA trial participants (N = 218) | All biopsy participants* (N = 78) | Placebo (N = 40) | Vitamin D (N = 38) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | % | N | % | N | % | N | % | |||||
Ethnicity | ||||||||||||
Non-Hispanic White | 190 | 87.2% | 72 | 92.3% | 36 | 90.0% | 36 | 94.7% | ||||
Non-Hispanic Black | 14 | 6.4% | 3 | 3.9% | 2 | 5.0% | 1 | 2.6% | ||||
Other (American Indian, Asian) | 14 | 6.4% | 3 | 3.9% | 2 | 5.0% | 1 | 2.6% | ||||
Education | ||||||||||||
College graduate | 85 | 39.0% | 21 | 26.9% | 14 | 35.0% | 7 | 18.4% | ||||
Graduate degree | 76 | 34.9% | 29 | 37.2% | 15 | 37.5% | 14 | 36.8% | ||||
High school or vocational training | 7 | 3.2% | 7 | 9.0% | 4 | 10.0% | 3 | 7.9% | ||||
Some college or associate degree | 50 | 22.9% | 21 | 26.9% | 7 | 17.5% | 14 | 36.8% | ||||
N | MEAN | SD | N | MEAN | SD | N | MEAN | SD | N | MEAN | SD | |
Age (year) | 218 | 59.6 | 5.1 | 78 | 59.3 | 5.2 | 38 | 59.3 | 5.6 | 40 | 59.3 | 4.8 |
Weight (kg) | 218 | 87.7 | 16.3 | 78 | 89.6 | 16.8 | 38 | 89.1 | 16.1 | 40 | 90.2 | 17.7 |
BMI (kg/m2) | 218 | 32.4 | 5.8 | 78 | 32.8 | 6.0 | 38 | 32.8 | 5.5 | 40 | 32.7 | 6.4 |
Waist circumference (cm) | 218 | 100.1 | 12.3 | 78 | 101.7 | 13.5 | 38 | 101.6 | 12.3 | 40 | 101.8 | 14.6 |
Hip circumference (cm) | 218 | 116.6 | 12.2 | 78 | 118.0 | 13.2 | 38 | 118.4 | 12.3 | 40 | 117.6 | 14.1 |
Body fat (kg) | 215 | 41.6 | 10.4 | 76 | 42.5 | 10.4 | 37 | 42.1 | 10.3 | 39 | 42.8 | 10.7 |
Body fat (%) | 215 | 47.4 | 4.9 | 76 | 47.7 | 5.1 | 37 | 47.7 | 5.2 | 39 | 47.7 | 5.1 |
Lean mass (kg) | 215 | 41.4 | 5.8 | 76 | 41.7 | 5.9 | 37 | 41.3 | 5.4 | 39 | 42.1 | 6.4 |
Pedometer steps/day (7 d average) | 214 | 5629 | 3263 | 76 | 5324 | 2933 | 36 | 5741 | 3204 | 40 | 4949 | 2651 |
Moderate to vigorous activity (min/week) | 218 | 142 | 143 | 78 | 148 | 143 | 38 | 112 | 105 | 40 | 181 | 165 |
Average caloric intake (kcal/day)a | 206 | 2004 | 699 | 73 | 1946 | 677 | 37 | 1971 | 760 | 36 | 1920 | 590 |
Relative % calories from fat | 206 | 33.0 | 6.2 | 73 | 34.3 | 6.8 | 37 | 35.4 | 7.8 | 36 | 33.1 | 5.5 |
Relative % calories from protein | 206 | 17.6 | 3.2 | 73 | 17.8 | 3.6 | 37 | 17.1 | 3.0 | 36 | 18.5 | 4.0 |
Relative % calories from carbohydrate | 206 | 48.3 | 7.4 | 73 | 47.5 | 7.7 | 37 | 48.3 | 8.0 | 36 | 46.5 | 7.5 |
Estrone (pg/ml) | 218 | 44.6 | 19.8 | 78 | 42.8 | 18.2 | 38 | 40.6 | 18.5 | 40 | 45.0 | 17.8 |
Estradiol (pg/ml) | 218 | 15.5 | 19.4 | 78 | 12.7 | 6.2 | 38 | 12.4 | 6.5 | 40 | 12.9 | 5.9 |
Leptin (ng/mL) | 218 | 40.3 | 18.9 | 78 | 41.2 | 19.8 | 38 | 41.4 | 19.4 | 40 | 40.9 | 20.3 |
Adiponectin (μg/mL) | 218 | 12.4 | 6.1 | 78 | 12.0 | 5.4 | 38 | 12.4 | 5.3 | 40 | 11.6 | 5.6 |
IL_6 (pg/ml) | 217 | 7.2 | 19.8 | 78 | 5.7 | 5.8 | 38 | 5.7 | 5.6 | 40 | 5.7 | 6.1 |
TNFa (pg/ml) | 217 | 10.4 | 4.7 | 78 | 9.9 | 4.0 | 38 | 9.7 | 4.1 | 40 | 10.2 | 3.9 |
IL_10 (pg/ml) | 217 | 53.7 | 386.6 | 78 | 22.9 | 22.8 | 38 | 20.2 | 17.2 | 40 | 25.4 | 27.0 |
IL_8 (pg/ml) | 217 | 13.5 | 64.9 | 78 | 13.9 | 62.0 | 38 | 20.9 | 88.8 | 40 | 7.2 | 3.8 |
Insulin (µu/ml) | 218 | 12.5 | 6.8 | 78 | 12.6 | 6.3 | 38 | 12.6 | 6.2 | 40 | 12.7 | 6.5 |
C-reactive protein (mg/ml) | 218 | 4.7 | 8.7 | 78 | 3.8 | 3.9 | 38 | 3.9 | 3.9 | 40 | 3.7 | 4.1 |
Serum 25(OH)D (ng/mL) | 218 | 21.4 | 6.1 | 78 | 20.5 | 6.5 | 38 | 21.6 | 6.1 | 40 | 19.4 | 6.8 |
