Table 3 Associations (Pearson correlation coefficients) between 12-month changes in gene expression in RPFNA and abdominal adipose tissue

From: Gene expression in breast and adipose tissue after 12 months of weight loss and vitamin D supplementation in postmenopausal women

Vitamin D (2000 IU/day) Arm (N = 28)

  

12-month gene expression changes in breast tissue (RPFNA)

  

ADIPOQ

CYP19A1

VDR

PPARg

MCP-1

12-Month gene expression changes in abdominal adipose tissue (AB)

ADIPOQ

0.067*

−0.055

0.164

−0.016

−0.143

  

0.735**

0.782

0.403

0.936

0.467

 

CYP19A1

−0.132

0.444

0.030

−0.118

−0.073

  

0.503

0.018

0.881

0.549

0.710

 

VDR

0.005

0.144

0.307

0.140

0.176

  

0.981

0.466

0.112

0.479

0.369

 

PPARg

−0.011

−0.029

0.249

0.064

−0.278

  

0.955

0.885

0.202

0.746

0.152

 

MCP

−0.126

0.032

0.197

−0.158

−0.018

  

0.523

0.873

0.315

0.423

0.928

Placebo arm (N = 33)

12-Month gene expression changes in abdominal adipose tissue (AB)

ADIPOQ

0.105

0.144

−0.061

0.004

0.026

  

0.562

0.423

0.737

0.982

0.886

 

CYP19A1

−0.168

−0.010

0.010

−0.134

−0.064

  

0.350

0.956

0.956

0.457

0.724

 

VDR

0.013

0.105

−0.117

0.017

0.007

  

0.941

0.562

0.517

0.924

0.971

 

PPARg

−0.144

0.048

−0.035

−0.073

−0.178

  

0.423

0.790

0.848

0.688

0.321

 

MCP

−0.155

−0.220

0.241

−0.211

−0.200

  

0.388

0.218

0.177

0.239

0.264

  1. * Correlation coefficient; ** P value
  2. AB adipose biopsy, RPFNA random periareolar fine needle aspiration