Table 3 Associations (Pearson correlation coefficients) between 12-month changes in gene expression in RPFNA and abdominal adipose tissue
Vitamin D (2000 IU/day) Arm (N = 28) | ||||||
|---|---|---|---|---|---|---|
12-month gene expression changes in breast tissue (RPFNA) | ||||||
ADIPOQ | CYP19A1 | VDR | PPARg | MCP-1 | ||
12-Month gene expression changes in abdominal adipose tissue (AB) | ADIPOQ | 0.067* | −0.055 | 0.164 | −0.016 | −0.143 |
0.735** | 0.782 | 0.403 | 0.936 | 0.467 | ||
CYP19A1 | −0.132 | 0.444 | 0.030 | −0.118 | −0.073 | |
0.503 | 0.018 | 0.881 | 0.549 | 0.710 | ||
VDR | 0.005 | 0.144 | 0.307 | 0.140 | 0.176 | |
0.981 | 0.466 | 0.112 | 0.479 | 0.369 | ||
PPARg | −0.011 | −0.029 | 0.249 | 0.064 | −0.278 | |
0.955 | 0.885 | 0.202 | 0.746 | 0.152 | ||
MCP | −0.126 | 0.032 | 0.197 | −0.158 | −0.018 | |
0.523 | 0.873 | 0.315 | 0.423 | 0.928 | ||
Placebo arm (N = 33) | ||||||
12-Month gene expression changes in abdominal adipose tissue (AB) | ADIPOQ | 0.105 | 0.144 | −0.061 | 0.004 | 0.026 |
0.562 | 0.423 | 0.737 | 0.982 | 0.886 | ||
CYP19A1 | −0.168 | −0.010 | 0.010 | −0.134 | −0.064 | |
0.350 | 0.956 | 0.956 | 0.457 | 0.724 | ||
VDR | 0.013 | 0.105 | −0.117 | 0.017 | 0.007 | |
0.941 | 0.562 | 0.517 | 0.924 | 0.971 | ||
PPARg | −0.144 | 0.048 | −0.035 | −0.073 | −0.178 | |
0.423 | 0.790 | 0.848 | 0.688 | 0.321 | ||
MCP | −0.155 | −0.220 | 0.241 | −0.211 | −0.200 | |
0.388 | 0.218 | 0.177 | 0.239 | 0.264 | ||