Table 1 Histologic features of phyllodes tumors according to the presence of fibroadenoma-like areas

From: Phyllodes tumors with and without fibroadenoma-like areas display distinct genomic features and may evolve through distinct pathways

Histologic parameter

PT with FA-like areas (n=7)

PT without FA-like areas (n=9)

p value

Tumor border

Well defined

4 (57%)

3 (33%)

0.592

Permeative

3 (43%)

6 (67%)

 

Stromal cellularity

Mild

1 (14%)

0 (0%)

0.212

Moderate

4 (57%)

3 (33%)

 

Marked

2 (29%)

6 (67%)

 

Stromal atypia

Mild

1 (14%)

1 (11%)

0.633

Moderate

5 (71%)

4 (44%)

 

Marked

1 (14%)

4 (44%)

 

Mitoses/10 HPF

0–10

6 (86%)

2 (22%)

0.04

>10

1 (14%)

7 (78%)

 

Stromal overgrowth

Absent

6 (86%)

5 (56%)

0.308

Present

1 (14%)

4 (44%)

 

Malignant heterologous elements

Absent

7 (100%)

7 (78%)

0.475

Present

0 (0%)

2 (22%)

 
  1. FA fibroadenoma, PT phyllodes tumor
  2. p-value according to Fisher’s exact test