Table 2 Odds ratios (95% confidence interval) of developing breast cancer by tertile and per each 10% increase in AR expression in normal breast tissue

From: Androgen receptor expression in normal breast tissue and subsequent breast cancer risk

 

Tertile 1

(≤10%)

Tertile 2

(11–30%)

Tertile 3

(>30%)

P trend

10% Increase

Cases/controls

19/63

31/108

28/105

 

78/276

Model 1

Ref

1.0 (0.5–1.9)

1.0 (0.5–2.0)

0.96

1.0 (0.9–1.1)

Model 2

Ref

1.0 (0.5–1.9)

0.9 (0.4–1.8)

0.68

1.0 (0.9–1.1)

  1. Model 1: Adjusting for age at breast cancer diagnosis/index date (<45, 45–54, and 55+), year of the BBD diagnosis (before 1980, 1980–1989, 1990 or later), and years elapsed between BBD diagnosis and breast cancer diagnosis/index date (0.5–4.9, 5–9.9, 10–14.9, and 15.0+)
  2. Model 2: Adjusted for covariates in Model 1 + BBD lesion type (non-proliferative, proliferative without atypia, and atypical hyperplasia)
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