Table 3 Associations between self-reported diabetes history and mortality and the role of fructosamine as a mediator, the New Mexico HEAL Study

From: Fructosamine and diabetes as predictors of mortality among Hispanic and non-Hispanic white breast cancer survivors

Diabetes history

All women

(N = 399)

Hispanic

(N = 96)

Non-Hispanic white

(N = 303)

All-cause mortality

Deaths

HR

95% CI

Deaths

HR

95% CI

Deaths

HR

95% CI

 None

109

1.00

Reference

22

1.00

Reference

87

1.00

Reference

 Yes

21

2.10

1.24–3.55

8

3.07

1.05–8.94

13

1.67

0.86–3.24

 % Explained by fructosaminea

 

1.57 (47%)

0.86–2.87

 

1.90 (56%)

0.61–5.96

 

1.52b

0.70–3.28

Breast cancer mortality

Deaths

HR

95% CI

Deaths

HR

95% CI

Deaths

HR

95% CI

 None

44

1.00

Reference

13

1.00

Reference

31

1.00

Reference

 Yes

8

2.89

1.27–6.60

3

2.52

0.59–10.79

5

2.18

0.73–6.52

 % Explained by fructosaminea

 

2.09 (41%)

0.80–5.46

 

2.06b

0.58–7.34

 

1.73b

0.34–8.74

  1. Models adjusted for age, BMI, stage, education, treatment, and ethnicity (among all women)
  2. aModels adjusted for age, BMI, stage, education, treatment, ethnicity (among all women), and fructosamine (continuous)
  3. bPercent (%) explained by fructosamine was not calculated since the associations for the main effects for diabetes and mortality outcomes were not statistically significant by ethnicity for breast cancer mortality and among NHW women for all-cause mortality
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