Fig. 1 | npj Breast Cancer

Fig. 1

From: AKT1low quiescent cancer cells in ductal carcinoma in situ of the breast

Fig. 1The alternative text for this image may have been generated using AI.

AKT1low QCCs are found within DCIS. a Hematoxylin and eosin stained section showing a representative area of ductal carcinoma in situ; b Multiplex immunofluorescence of DCIS tissue shown in a with AKT1low QCC cluster marked by a white arrow and the marker profile: AKTlow (green), H3K9me2low (yellow) and HES1high (red); inset image is enlarged to show QCC marker detail. c Digital tumor map of DCIS tissue shown in a and b with AKT1low QCCs shown in red and proliferating cancer cells in blue. Images were taken at ×20

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