Fig. 5
From: LobSig is a multigene predictor of outcome in invasive lobular carcinoma
Features of LobSig-stratified tumors. a Genetic landscape shown in scatterplot of gene-centric mutations and driver alterations that characterize the LobSig high-risk group. Samples analyzed were grade 2 ILC tumors in the METABRIC and RATHER cohorts (n = 108). Significance represented by dot size; mutations in green, amplifications in red, deletions in blue. b Gene Ontology analysis of the genes differential expression between LobSig high and low tumors is visualized with REVIGO, where the X and Y distance means similar terms are closer together. The terms generated using the METABRIC and TCGA cohorts were combined, and only those terms with a false discovery rate (FDR) of q < 0.002 were included in the REVIGO analysis. Note that the FDR is represented by size. Regn regulation
