Fig. 1 | npj Breast Cancer

Fig. 1

From: Quantitative assessments and clinical outcomes in HER2 equivocal 2018 ASCO/CAP ISH group 4 breast cancer

Fig. 1

Analysis of human epidermal growth factor receptor 2 immunohistochemistry (IHC) status by real-time quantitative reverse transcription polymerase chain reaction (RT-qPCR) and quantitative immunofluorescence. Distribution of RT-qPCR (a) and AQUA (b) scores in 2018 American Society of Clinical Oncology/College of American Pathologists in situ hybridization group 4 IHC 0/1+ and IHC 2+ tumors. Closed and open circle represent estrogen receptor-positive and -negative cases, respectively. Dotted line represents the threshold for RT-qPCR or AQUA. Significant P values are represented as four asterisks (****) for <0.0001

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