Fig. 5: Immune cell profiling of the microdissected breast stroma.
From: Upregulation of lipid metabolism genes in the breast prior to cancer diagnosis
a CIBERSORT immune cell fractions were determined for each subject. The mean value for NK cell fraction was calculated for each group and compared using two-sided unpaired t test. b Immunohistochemical (IHC) representative images (×40 magnification; scale bar: 200 µm) and quantification of CD45 and c CD20 staining in susceptible and matched healthy (HC) breast tissue sections; each dot represents one subject. Quantification of the staining was performed using QuPath 0.2.0 and expressed as the number of positive cells per mm2. Error bars show the standard error of the mean. *P < 0.05; **P < 0.005.
