Fig. 7: Spatial colocalisation patterns of TIL subset in adjacent DCIS samples in the IHC dataset.
From: Unmasking the immune microecology of ductal carcinoma in situ with deep learning

a Low power CD4, CD8, FOXP3 IHC images of a sample and high-resolution images of a region of DCIS showing single-cell detection and classification using DRDIN and SCCNN. b Boxplots showing differences in DCIS immune colocalisation score between CD8+, CD4+ and FOXP3+ cells using paired tests. c Boxplots showing the difference in CD8+ cell colocalisation between DCIS and invasive epithelium indicating differential immune response within the same sample in different compartments. DCIS immune colocalisation score is referred to as Morisita to conserve space in the representation.