Table 1 Characteristics of the study sample.

From: The acute effects of adjuvant radiation and chemotherapy on peripheral blood epigenetic age in early stage breast cancer patients

 

Radiation therapy alone (N = 37)

Chemotherapy and radiotherapy (N = 35)

Total (N = 72)

p-Valuea

Demographic characteristics

Age (years), mean ± SD

57.3 ± 9.3

56.1 ± 11.2

56.7 ± 10.2

0.44

Ethnicity, N (%)

 Hispanic

5 (14)

2 (6)

7 (10)

0.47

 Non-Hispanic

32 (86)

33 (94)

65 (90)

Education, N (%)

 HS degree

8 (22)

8 (23)

16 (22)

0.41

 College degree

12 (43)

16 (46)

28 (39)

 Postgraduate degree

17 (46)

11 (31)

28 (39)

Body mass index, mean ± SD

25.6 ± 5.3

25.7 ± 6.7

25.7 (6.0)

0.96

Tobacco smoking, N (%)

 Current

1 (3)

1 (3)

2 (3)

0.59

 Former

11 (30)

7 (20)

18 (25)

 Never

24 (65)

27 (77)

51 (71)

 

Menopausal status, N (%)

 Pre-menopausal

8 (22)

9 (26)

17 (24)

0.64

 Peri-menopausal

1 (3)

3 (8)

4 (5)

 Post-menopausal

26 (70)

22 (63)

48 (67)

 Hysterectomy

2 (5)

1 (3)

3 (4)

Tumor characteristics

 ER positive, N (%)

36 (97)

26 (74)

62 (86)

0.013

 PR positive, N (%)

32 (86)

21 (60)

53 (7)

0.023

 HER2 amplified, N (%)

2 (5)

2 (6)

4 (5)

0.95

Stage, N (%)

 0

5 (13)

0 (0)

5 (7)

0.00015

 1

25 (68)

11 (31)

36 (50)

 2

7 (19)

18 (51)

25 (35)

 3

0 (0)

5 (14)

5 (7)

Type of surgery

 Lumpectomy

35 (94)

27 (77)

62 (86)

0.032

 Mastectomy

2 (5)

8 (23)

10 (14)

  1. ap-Value comparing treatment groups.
  2. p-values were in bold if < 0.05.