Fig. 2: Relationship between individual participant estradiol or estrone levels and BMI.

a Baseline BMI (kg/m2) distribution of all patients (gray, n = 112) and those with BMI > 25 kg/m2 who continued to the second 28-day interventional period (red, n = 31) b Association of day 29 estradiol with baseline BMI. c Association of day 29 estrone with baseline BMI. Dashed line represents mean value.