Fig. 2: Enrichment of gene ontology sets among genes correlating with IGHA2 and IGHG1 mRNAs. | npj Breast Cancer

Fig. 2: Enrichment of gene ontology sets among genes correlating with IGHA2 and IGHG1 mRNAs.

From: Prognostic implications of the expression levels of different immunoglobulin heavy chain-encoding RNAs in early breast cancer

Fig. 2: Enrichment of gene ontology sets among genes correlating with IGHA2 and IGHG1 mRNAs.

All mRNAs in the SCAN-B cohort were analyzed for correlation with IGHA2 and IGHG1 mRNA expression. The top 100 correlating genes for each IG mRNA were selected for enrichment analysis. The enrichment was analyzed performed using the Biological Process sets defined by the Gene Ontology Consortium. Fisher’s test was used to evaluate enrichment. The graph shows the −log10 of the p value from the Fisher’s tests of indicated Gene Ontology Biological Process gene sets for the top 100 IGHA2- (blue) and IGHG1- (red) correlating genes. Results are shown for gene sets with a p value < 10–15 for either IGHA2- or IGHG1-correlating genes.

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