Fig. 3: Expression of Ig heavy chain-encoding RNAs in relation to clinico-pathological parameters.

Box and scatter plots of the log2 expression levels of indicated RNA species in relation to ER status, HER2 amplification, NHG grade, PAM50 subtypes, and age at diagnosis for the SCAN-B cohort. The p values were calculated with the t-test comparing positive with negative status (ER and HER2) and grade 1 versus grade 3. For age the p value was extracted from linear regression modeling using tlm function in R. The PAM50 subtypes are basal (B), HER2-enriched (H2), luminal A (LA), luminal B (LB), and normal-like (N). In box plots the center line marks the median; box limits mark the upper and lower quartiles; whiskers mark 1.5x interquartile range; points mark outliers beyond this mark.